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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ab07105b3f49e719ef1404761ee8f152caa8790d07e3a80f7c3a55f52bf0a3f' 
  AND token = 'F7kHhs9sS6MKmwCc5Siwe4VHnpbeHM8UE+b6raS2t7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}