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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ad26fbd765e7b80cfdbee4e6b29b833dcc78e89e10d2d1b489f65fb3caa8ef0' 
  AND token = 'BEDH8zItKuA/tpaYWnYixL5rn2cBQ0wxLXgVN0+X2yM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}