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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eaeeb0c94e9caa65524cf00ba2b25bf8d494c285eb6e3376e1c7c7734017e354' 
  AND token = '+73c5Usp60z+0x3ZRPWaUZ5N4BPEYKMsqSvDf0sxu3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}