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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e320917805569186f6fe7de60c05165e04e08232456d440c0f6c33b21494d5c9' 
  AND token = 'OVoEH5L2rrrJXmJ1k6Q/RoZRO5HYm8qcVmSvW7VFiZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}