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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3be3e8a275f31f4eea2be21e6c53f1bb4c535f8814771d38742315a71ac194ce' 
  AND token = 'DhxLE/wDiojeIb7QHAW+H/iDPaYa3zJ500uvEySAwqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}