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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '740b73bed9a55425bd6c86e347712f8c38ac2d0e8643e21aebe7c51a7ebe40fe' 
  AND token = '+N6I8/NLgvGDf1L4Hu8y5VK8zXW3EH7DYG6QsN692eQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}