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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bf9159abe965d49960685e6f09be96a1d1aba8d176f698dcdb57f201c4a8711' 
  AND token = 'sSQJ4MgWB+2YzHDQ/EClQy3w2oXI0Qa2PxaXu8GIXsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}