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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ffaabf781a6e1b0f0300511f312c8fa24704a975341d17fa1624ee0c9b93ee6' 
  AND token = '59f181poGAOWFtpsYGT9kOL/z3ndjWrG9GrGyDOGRw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}