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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ed22113eb0ad6279eb0c96e15c1eb13812f51d3c709964281590bc957b55b58' 
  AND token = 'UE6SGN+pMI4LLJ+TxrP9c+3B3jkpUWPKVrKskZGhDkw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}