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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63ff2f6405786eced815ec5cc869ebcf505302fc4868eab6c4163331512c5700' 
  AND token = 'TkZ9itk5TAZt49noGpb+Ha962FJf4AawlIf0nyDAaCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}