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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44633d143b298d0fa4ae0f61fc948dd5982b2a7c1990719104064516f35ee3a8' 
  AND token = 'AKz8vagzdabSgJVtQdV7Va8yB1BpHqMITyOPohvLoaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}