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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df9170bd80ae78652fcda529a7fc9b77d660d00c68e8c5bc5981b668a25192c7' 
  AND token = 'q4tmp4ocZycZOlk5yRxQugHc/WBgb/dgBLnpE6/aUaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}