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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08a01da6fb6478d8cebac8d7e0e7ccc968016529e77df34315634c956d0253ff' 
  AND token = '+TQ65ecw9NzZ9ci6ulpzX1nlGvlWWThWr+P5mcIX1cg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}