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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b63cc125d41dcd10569e582775eccbd855a1bc31b388c5e0aa55f1d6656c2226' 
  AND token = 'Jyx5h4PsHcf91biUexKUbvWuuBSneW7LK5YuiHneP1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}