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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1800834232fbfda3d51c03b4215be2c837437668cfb8626677670d473fe3fe16' 
  AND token = 'XZNp1U9Xpn2/dQrimG8fhxx6NqmpLp2iP6L+PzwMk3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}