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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53c4d9917915cbc05d50943929064f946980a32684dc392c6e72b9f414275428' 
  AND token = 'B47eg9T62ED9Eagy5qu2sqDaE1wL9gZTXAo1yrA2x6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}