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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b89f0645778d9f37fa4c984a6d85ffeee38684d0078ddec4846069bf3b51743' 
  AND token = '5U4OZIAp3MlKnM6WPl3CeNdyHyyN52Vl+Sg7n4NV7Nk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}