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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18059c0fd7d7925d0b02734e333aebb01500775de344322f121b519f5c8993a1' 
  AND token = 'jqW/pAw/I0MXnKzSWWpKH6uw1n3R8lERTI5K6nYS1GA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}