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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14289bd5a19b591a11e557fefcba095fbbcf1af64762fd9a4ad3da833480a3d7' 
  AND token = 'nVyEwua5i+M2uJ6IueUvgt6tswwp01mNhPHxkSkT+Ek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}