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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '859485b5b4bc8a2518c138de3ee7fe9f0591df1d044babac611758930a3acbb9' 
  AND token = 'D2pdg3endwI4knwdEaCR3l+IlwPqhw63+gjx/mGCoU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}