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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f44139718015f5e8b326908d0c0bbcc37f967f98800a9dc60b51a92a456b7fdb' 
  AND token = 'dCIWIPdDxiAuOKm1WiSxk7cjy5vcfaWvSsjXPfSi0xQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}