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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '245b83059289bc39472d7c11ab0982374fd9aa6911b96c2ac444250b61b1e1e0' 
  AND token = 'OHeJvP1RGrIlau2lSOq1qjlIxoeDTS1TPzFCFo8EK2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}