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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ab09e9163520f33a8040f2d75e8bbd0e883834e98f0aedd1b93fb422be05fd7' 
  AND token = 'e7iXqmd0BcaTSPve0uNN5c0umV1W1J8GBxLAPBa5Sc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}