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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10b677d7248f5c6117901e4b3b1a7fed0882de817d73d5b34541ab44ad282cf4' 
  AND token = 'oWI737VQoHcstB43/xphxmRbbWwmMaq5miJrBvV65/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}