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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b787ae9510fbe8f8f9842cc80d78cffe58b4df64483d540784b0980652fa7649' 
  AND token = 'Gt/3ykyBQ07z5PxCZY5gT5crfc/acjhj0eRZbYAI3Fo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}