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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78efb871017becdd6693d3d5b056ec2c7dfed0b37a0c50a9dca6fabbe4fc9dd1' 
  AND token = 'f9hhvk8J9TwQ6Wyd4Mhf2gW5cF8qG1XR2ifnWUm8P7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}