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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c330f50731dcc37b7c03e960d2f016cc6adbd0715e4d96990de52e48d2ff6b49' 
  AND token = 'fIfvk8eeXtLen8DaVAmMF71S8XCmPPKCH7LWNBUVhGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}