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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f35195a64bb801c6bdff9acb07a8d56633c238df800eeb026c02dee46b67d95' 
  AND token = 'vtGYIm4ObVlzHEkWrX4Xpfl8pMavXkRbtC605P0VqRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}