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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15f5f9138f79512aef05ab3e4b856aed630d2ecfd5cf06a539a7b916c7c0f78d' 
  AND token = '2iip/YOa/nLp82J2obsA5+24idWOEokAHpkaJU7MEiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}