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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f3ac491dd05e5d8569d9dd043673fe6acd48c81b423389ba08516a50be6ab81' 
  AND token = 'NG/Ui9w7X9Ze2Hc7c5VjLdMEcfxFTVq3SNNM2N1zSF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}