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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ad6c25628de8406bfa7bd64a662d22fa04efe2f581583624d5049b94a406a8b' 
  AND token = 'yQ3Yt7IvP1jx3/DdcN+Ia/AUZ80iI3qeoyfGm6aopEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}