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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a55743449a66849828d7f466c8ab9981920aa09dbe3aafaa8ad7b92ce522ed5c' 
  AND token = 'Mn+Tfqwi3NOQJK6GRRDRjytsdOQ08tnVRWu1pOZb3zc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}