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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd818fe9b5668359cf165bcf2136bfd776d2b0ce699441b5ee69a06b2cb1ca2c7' 
  AND token = 'oUcXbzU2yDdCbqM+Ht1qco7D7Fgf1n/KosF0sLaO2GE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}