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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e5f121f42a5a9748e2b3df65e9c2029a90162fa8066ee8788757d7c0af5c4c7' 
  AND token = 'QE6abpXLIUhF/SPMYXNiRjtPTlCEC2D4ZuzWVcgC7WQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}