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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82178d8eb678a8a8f225f3fde671dcd0bf2057d248dbe5cca6a2afbb4109a25c' 
  AND token = 'HSadps6KRt1x/UYrBH76IaprDCEI+iJcN7JN3nF96os=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}