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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0951e6b89911448e6de911a75403a1ea2b120ffc2aeee46eee3bb41a2e382e0c' 
  AND token = 'Qv8z5aDcQUXJaUEp/Pqs0KA9T6zKuHv12brbMDB46KI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}