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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4609e281bf930b38aa84e94b98612c1a60012ab98ce3f857bab451163833c5fd' 
  AND token = 'oasX/9bY8N1H5Nx3kbwHJJFNpASzol2a+0OGWJd7Obw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}