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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2194682c65435d325874e7bc0404ecbed6084728c36c98538252fde92cbf73fe' 
  AND token = '0pY/QTmK62BZRuQk99aIW+aUp2ZM+zsoSd+DbQ62+5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}