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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1e349ac8971470167eba0273bf6b8ea02aa74114fdf23298e9906ff051c607b' 
  AND token = 'sdZdAxgNGsSHVzAyR8hQN270R4wj7IUwuBIxi9I4+rY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}