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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ad2daed14791c86f9492dd98007cd6a2d356481c0e064b77a311a861d61e7b2' 
  AND token = 'kvcCCB8sNs+m5vy+bSY0/nfZmPZdPoDLNSghaMCSEaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}