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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42b0a1956d1d17367b7413fa8a5644d6aa0b6f32ce71ca79f15da58cbaf6f1fa' 
  AND token = 'hOwQdV4VCD2WHyE1vYddPfevpHuenrm3DUDN8PPABWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}