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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01d2394bd29a1904f55f1664f2ae7eeaa9ad815d082e486ce343303712b21c02' 
  AND token = 'ilzJvaq6R036a82GMSptaVflu18nQzsxST3efqTEMdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}