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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5216730d039f650e85bc1c8a20b59bf361ebb726c788e899f93f56f6f4c33b6' 
  AND token = 'Db98Fo2qR5qqJreQVhXpVkewT4A8LpwW6YRMtqwrjSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}