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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2911a501da5f4838992ef4f55e98c705a68c6c81bd0a8dbb33e4bdd8b6d3f163' 
  AND token = 'V14+SrZDnNsPEdqD93kyvwtaUx9rdvF/HQdVvVZ1+9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}