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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40e950228167902f4cb0dc22e222ded5deaa0fc7b0d01512d2550363c732b845' 
  AND token = 'qfLa1M/hFw1fiYZRfTBtiUVsOh8RMXJM9eSGvcRipY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}