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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '588d45b0cd1ea48f1f0200d2cbb9845f90ffd0895cb0b60ad9ec241c4ad67fb8' 
  AND token = 'N8WUQnr54wflFIoZb4afgYBK6EPyxWm5FsdeuLj2Vvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}