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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e5bf2e7880477d62176965454adbad1a9e674eebe0d5ffe422f0b021b64cdec' 
  AND token = 'leo1O6BuLuq5MEc2p5cNwy20KUzFtRA1lajUl3mAbfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}