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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79ef2a0933f4994c3c56a66da856f50924e9dfe3e319bee42124bc51a286f594' 
  AND token = 'v44/+OhDrYO8BkeHDbQJxShE5YrxLUMSEOooEN+JXZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}