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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ec0705db743f934a692ec25b7fb41752ea7a37c36a9e14f5f5dc6b1618923c5' 
  AND token = '3l+jtGsrJDE+qkX4/1CGe7EN3vHjEMpy6DrZFEPObiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}