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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22f82dea2ff80d7f246d8ee1e94c43d3ee4e15da01935e19adfb709eb22d6ce7' 
  AND token = 'OXj+qYtXUeS796aof7al1VNwz77bNVzLM0Ur3U2tRDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}